ENDOGENOUS ANGIOTENSIN STIMULATION OF VASOPRESSIN (AVP) IN THE NEWBORN LAMB

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Ontogeny of blood pressure and the renin-angiotensin-aldosterone system. Sequential studies in the newborn lamb.

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Ontogeny of Blood Pressure and the Renin - Angiotensin - Aldosterone System Sequential Studies in the Newborn Lamb

To test the hypothesis that the rise in arterial pressure occurring with maturation is due to an increase in the vascular responsiveness to angiotensin II, sequential cumulative doses of angiotenmn II were infused intravenously into chronically catheterized newborn lambs maintained on a constant, weight-adjusted sodium intake from birth to 8 weeks of age. Basal mean arterial pressure correlated...

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Importance of plasma angiotensin concentrations in a comparative study of responses to angiotensin in the maturing newborn lamb.

Plasma angiotensin concentrations were measured in a longitudinal study of the vascular, renal, and adrenal responses to infusions of angiotensin II (AII) in the maturing newborn lamb. Basal plasma concentrations of angiotensin increased with age and correlated with the rising arterial pressure that occurred with maturation. However, age was a stronger determinant of arterial pressure than was ...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1977

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-197704000-00374